December 7, 2025
SITC 2025 Leukemia Acute Lymphoblastic Leukemia News

Natural killer T-cells show promise for ‘off-the-shelf’ cancer immunotherapy for NHL, ALL

Allogeneic natural killer T cells (NKTs) expressing CD19-specific chimeric antigen receptors (CARs) are well tolerated and can mediate objective responses in non-Hodgkin’s lymphoma

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Multiple Myeloma Video Interviews

Dr. Mateos discusses blenrep/DREAMM-7 trial

Dr. Mateos was the lead investigator on the trial, which investigated belantamab mafodotin (blenrep) with bortezomib and dexamethasone (BVd) versus daratumumab with bortezomib

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Leukemia Acute Myeloid Leukemia

Novel AML product candidate granted orphan drug designation by FDA

Novel product candidate M2T-CD33 (LTI-214) was granted orphan drug designation by the US Food and Drug Administration for the treatment of acute myeloid

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Leukemia News SOHO 2025

Dr. Jabbour discusses investigational menin inhibitor bleximenib

In this interview at the Thirteenth Annual Meeting of the Society of Hematologic Oncology (SOHO 2025), Elias Jabbour, MD, leukemia professor at the

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Leukemia News SOHO 2025 Leukemia Chronic Lymphocytic Leukemia

Obesity increases infection risk in CLL for patients treated with a BTKi

Patients with chronic lymphocytic leukemia (CLL) who have a body mass index (BMI) of 40 or higher (obesity class 3) are at a

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Leukemia Chronic Lymphocytic Leukemia SOHO Insider Podcast

Drs. O’Brien, Jain discuss FLAIR trial, BTK degraders in CLL

In this episode of the SOHO Insider podcast, Susan O’Brien, MD, a professor of medicine from the Chao Family Comprehensive Cancer Center at

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Leukemia Acute Myeloid Leukemia

FDA approves revumenib in relapsed or refractory NMP1-mutated AML

The US Food and Drug Administration (FDA) has approved revumenib (Revuforj®) in patients with relapsed or refractory NPM1-mutated acute myeloid leukemia (AML). The

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ESMO 2025 Acute Lymphoblastic Leukemia Aggressive B-Cell Lymphomas Multiple Myeloma Myelodysplastic Syndromes

Despite digital advances, cancer research remains costly, burdensome

Clinical cancer research remains too expensive and too burdensome, even amid a proliferation of digital tools designed to improve it, according to Ines

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ESMO 2025 Myelodysplastic Syndromes News

Bexmarilimab continues to show strong efficacy in phase 1/2 trial update

Updated results from a phase 1/2 trial of bexmarilimab plus azacitidine continue to support the efficacy of the combination in treatment-naïve patients with

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MDS News SOHO 2025 News

VERONA phase 3 trial shows no survival benefit in high-risk MDS

The study, presented by Guillermo Garcia-Manero, MD, interim chair of the Department of Leukemia at the University of Texas MD Anderson Cancer Center,

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