Save the date: SOHO 2027 scheduled for August 25–28
SOHO Insider Editors
September 24, 2026
SOHO 2027 is scheduled for August 25–28, 2027, in Houston, Texas at the George R. Brown Convention Center.
FDA approves 1st new treatment for essential thrombocythemia in nearly three decades
SOHO Insider Editors
September 24, 2026
The FDA’s decision was primarily supported by clinical data from the global phase 3 SURPASS-ET clinical trial, which demonstrated that the therapy achieved durable modified European LeukemiaNet responses and robust hematologic control.
Posters not to miss: cellular therapy edition
Krish Patel, MD
September 24, 2026
Dr. Krish Patel reviews key cellular therapy posters at SOHO 2026, featuring studies on CAR-T mortality, circulating tumor DNA in follicular lymphoma, and real-world outcomes for chronic lymphocytic leukemia.
Dose-dense mini-CVD plus inotuzumab ozogamicin, blinatumomab demonstrates deep, durable responses in relapsed or refractory B-ALL
Patrick Daly
September 23, 2026
The analysis, led by Hannah Goulart, MD, of The University of Texas MD Anderson Cancer Center in Houston Texas, was presented at the Fourteenth Annual Meeting of the Society of Hematologic Oncology in Houston, Texas.
FDA receives sNDA for selinexor, ruxolitinib in myelofibrosis
SOHO Insider Editors
September 22, 2026
The submission is based on data from the phase 3 SENTRY trial, which evaluated the combination in JAK inhibitor-naive patients and demonstrated spleen volume reduction and an overall survival signal.
LYT-200 receives FDA Fast Track Designation for relapsed or refractory high-risk MDS
SOHO Insider Editors
September 22, 2026
Feedback from the FDA supports advancing the therapy into STRIDE-MDS, a randomized, double-blind, placebo-controlled phase 2 clinical trial evaluating the efficacy, safety, and dose selection of LYT-200.
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