The Society of Hematologic Oncology (SOHO) was established as a non-profit corporation in 2012 with aims to promote worldwide research, education, prevention, clinical studies and optimal patient care in all aspects of hematologic malignancies and related disorders.
The US Food and Drug Administration (FDA) has approved and launched a new prefilled pen device for ropeginterferon alfa-2b-njft (BESREMi Pen) for adult patients with
Dr. Banerjee reviewed the BCMA-sparing clinical efficacy data from the trial and discussed the results, which showed that MeziKd significantly extended progression-free survival while offering a crucial option before or after T-cell engager therapies.
In this multiple myeloma roundtable from EHA 2026, the roundtable panelists evaluate the strategic sequencing of mezigdomide-based therapy, its potential as a bridging strategy, and its practical logistical advantages in community-based practices compared to T-cell redirecting therapies.
The therapeutic indication covers patients undergoing matched donor hematopoietic stem cell transplantation (HSCT) alongside a myeloablative preparative regimen to facilitate immunologic reconstitution and improve chronic graft-versus-host disease-free survival.
Clinical investigators are actively evaluating these novel agents across several strategic combinations and settings, Prof. Weisel explained.
“We have very interesting maintenance trials,” she noted, “where iberdomide is tested as a monotherapy or even in combination with monoclonal anti-CD38 antibodies.”
In this roundtable discussion on myeloma and CELMoDs, the panel discuss mechanism of action, overcoming drug resistance, and other distinguishing features of this novel group of treatment agents.
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