
Tri-specifc CAR-T shows early activity in B-cell malignancies
The Phase 1 trial evaluates DuoCAR20.19.22-D95 in adults with relapsed or refractory B-cell malignancies who have often failed prior CAR T-cell treatments.
The Society of Hematologic Oncology (SOHO) was established as a non-profit corporation in 2012 with aims to promote worldwide research, education, prevention, clinical studies and optimal patient care in all aspects of hematologic malignancies and related disorders.

The Phase 1 trial evaluates DuoCAR20.19.22-D95 in adults with relapsed or refractory B-cell malignancies who have often failed prior CAR T-cell treatments.

Researchers conducted a systematic review of phase III trials to assess the correlation between these two endpoints in MCL studies. The final analysis included 16 trials assessing 19 treatment options in nearly 6,000 adult patients.

This issue of SOHO Insider features an article on US patient representation in global trials, an interview with Dr. Naval Daver, and photos from SOHO

In this session from the SOHO Insider Community Oncology Brown Bag series, Luke Fletcher, MD, presents on an exploration of barriers and solutions for activating

The discussion also covers the study’s safety profile and the potential for these early-stage immunotherapies to achieve long-term curative results.

The oral combination is used with venetoclax for patients who are at least 75 years old or have other medical conditions that prevent the use of intensive chemotherapy.
SOHO Insider is the official media platform of the Society of Hematologic Oncology. The SOHO Insider Editorial Board is comprised of leading hematologists. Learn more about our editorial board and SOHO Insider platforms.
Submit your difficult clinical questions to the Ask-the-Expert forum in the SOHO mobile app. Submit your questions in our exclusive members-only forums community on the SOHO mobile app. Your inquiry will be sent directly to leading experts, including Dr. Hagop Kantarjian, Dr. Kami Maddocks, Dr. Sagar Lonial, and Dr. Mascarenhas for their insights.
Follow the instructions below to ask a question now!
Benefits of membership include:
The Career Center provides SOHO members with the ability to find jobs in the field of Hematologic Oncology along with a variety of career advice. Select the 'Career Center' button to explore new job opportunities and career information.
The Career Center Allows SOHO Members to:
To access the SOHO Career Center click the following link.