FDA ODAC votes 8-1 glofitamab trial does not apply to US patients
A federal advisory panel voted 8-1 Tuesday that results from the global STARGLO trial, which was intended as the confirmatory trial for full
Lymphoma
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News
SOHO Insider Podcast
Gwen Nichols speaks with Saad Usmani on CAR-T therapy advances
Saad Usmani, MD, of Memorial Sloan Kettering Cancer Center in New York, and Gwen Nichols, MD, CMO of the Leukemia & Lymphoma Society
Myelodysplastic Syndromes
Study identifies nonmutational p53 dysfunction as MDS risk factor
Even in patients with myelodysplastic syndromes (MDS) who don’t have a mutation in tumor protein 53 (p53), the p53 protein might still be
Leukemia
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Video Interviews
Dr. Wu highlights global disparities in leukemia mortality
In this video, James Wu, MD, a hematology/oncology fellow at the Medical College of Wisconsin, discusses a letter published in the journal Leukemia
Leukemia
Video Interviews
Ching-Hon Pui, MD, on the global effort to treat pediatric leukemia
Dr. Pui, co-leader of the hematological malignancies program at the St. Jude Children’s Research Hospital in Memphis, Tennessee, shares his gratitude for receiving
Lymphoma
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Bispecific–ADC duo yields responses in aggressive Burkitt’s lymphoma
Three patients with chemotherapy-refractory Burkitt’s lymphoma achieved complete metabolic responses after treatment with glofitamab and polatuzumab vedotin, according to a recently published correspondence
Cellular Therapy
2025 AACR Annual Meeting
Multiple Myeloma
Trispecific therapy ISB 2001 active in ongoing early myeloma trial
ISB 2001, a trispecific T-cell engager targeting BCMA and CD38, showed expected immune activity and no dose-limiting toxicities in an ongoing phase 1
Leukemia
2025 AACR Annual Meeting
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RNA-seq maps genetic, nongenetic drivers of AML
Investigators used RNA sequencing to create a new gene activity atlas that showed how normal blood cells developed. The technique also identified the
Lymphoma
Multiple Myeloma
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Spain’s POC manufacturing model reimagines CAR-T delivery
While the US relies on centralized, commercial CAR-T manufacturing, Spain is taking a different approach. At Hospital Clínic de Barcelona, point of care
Leukemia
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Pathways & Perspectives with Charles Craddock, CBE
Dr. Craddock talks life in general and about the past and future of blood cancer treatments.