December 9, 2025
Multiple Myeloma News

FDA panel votes 6-2 in favor of daratumumab for high-risk smoldering multiple myeloma

The US Food and Drug Administration (FDA)’s Oncologic Drugs Advisory Committee (ODAC) voted 6-2 that the results from the phase 3 AQUILA trial

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Ambassador Program News Society Updates

SOHO Israel 2025 wraps up successful 2-day event with leading hematologists

The third meeting of SOHO Israel and 9th International Davidoff conference, titled State of the Art and Next Questions, was held on May

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Lymphoma News

FDA ODAC votes 8-1 glofitamab trial does not apply to US patients

A federal advisory panel voted 8-1 Tuesday that results from the global STARGLO trial, which was intended as the confirmatory trial for full

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News SOHO Insider Podcast

Gwen Nichols speaks with Saad Usmani on CAR-T therapy advances

Saad Usmani, MD, of Memorial Sloan Kettering Cancer Center in New York, and Gwen Nichols, MD, CMO of the Leukemia & Lymphoma Society

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Myelodysplastic Syndromes

Study identifies nonmutational p53 dysfunction as MDS risk factor

Even in patients with myelodysplastic syndromes (MDS) who don’t have a mutation in tumor protein 53 (p53), the p53 protein might still be

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Leukemia News Video Interviews

Dr. Wu highlights global disparities in leukemia mortality

In this video, James Wu, MD, a hematology/oncology fellow at the Medical College of Wisconsin, discusses a letter published in the journal Leukemia

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Leukemia Video Interviews

Ching-Hon Pui, MD, on the global effort to treat pediatric leukemia

Dr. Pui, co-leader of the hematological malignancies program at the St. Jude Children’s Research Hospital in Memphis, Tennessee, shares his gratitude for receiving

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Lymphoma News

Bispecific–ADC duo yields responses in aggressive Burkitt’s lymphoma

Three patients with chemotherapy-refractory Burkitt’s lymphoma achieved complete metabolic responses after treatment with glofitamab and polatuzumab vedotin, according to a recently published correspondence

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Cellular Therapy 2025 AACR Annual Meeting Multiple Myeloma

Trispecific therapy ISB 2001 active in ongoing early myeloma trial

ISB 2001, a trispecific T-cell engager targeting BCMA and CD38, showed expected immune activity and no dose-limiting toxicities in an ongoing phase 1

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Leukemia 2025 AACR Annual Meeting News

RNA-seq maps genetic, nongenetic drivers of AML

Investigators used RNA sequencing to create a new gene activity atlas that showed how normal blood cells developed. The technique also identified the

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