July 11, 2025
66th American Society of Hematology Annual Meeting & Exposition Leukemia

Fixed-duration regimens outperform SOC in treatment-naïve CLL

Fixed-duration acalabrutinib plus venetoclax with or without obinutuzumab improved progression-free survival over fludarabine-cyclophosphamide-rituximab or bendamustine-rituximab in treatment-naïve chronic lymphocytic leukemia (TN CLL), according

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66th American Society of Hematology Annual Meeting & Exposition Leukemia

Asciminib benefit-risk profile bests other TKIs in CML

Results from the phase 3 ASC4FIRST study presented at the 2024 American Society of Hematology Annual Meeting & Exposition showed that asciminib had

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Meetings / Conferences 66th American Society of Hematology Annual Meeting & Exposition Lymphoma

Tafasitamab plus lenalidomide, rituximab improves PFS in patients with relapsed or refractory follicular lymphoma

Addition of tafasitamab, a humanized CD19-targeting monoclonal antibody (mAb), to lenalidomide plus rituximab resulted in significant and clinically meaningful improvement in progression-free survival (PFS),

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Meetings / Conferences MDS

Smoking associated with MDS mutations, progression

Results from a prospective study presented at the American Society of Hematology Annual Meeting & Exposition showed that tobacco smoking was associated with

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Society Updates

Save the date for SOHO 2025 in Houston, Texas

The Society of Hematologic Oncology (SOHO) has announced that its 2025 meeting will be held between Wednesday, September 3, 2025, and Saturday, September

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Cellular Therapy T-Cell Lymphoma

CTX130 demonstrates potential in relapsed or refractory T-cell lymphoma

The chimeric antigen receptor (CAR)-T cell therapy CTX130 (volamcabtagene durzigedleucel) showed encouraging results in patients with heavily pretreated relapsed or refractory T-cell lymphoma,

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Meetings / Conferences 66th American Society of Hematology Annual Meeting & Exposition

Novel immune checkpoint blocker ‘well-tolerated’ in DLBCL

FS118, a new potential immune checkpoint blocker, was well tolerated in patients with relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL) with

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Multiple Myeloma

MRD2STOP trial supports discontinuation of maintenance therapy in MM patients with low MRD negativity

Maintenance therapy discontinuation in patients with deep measurable residual disease (MRD) negativity (<10⁻⁶ or <10⁻⁷) is associated with low rates of disease resurgence

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Society Updates

Why join the Society of Hematologic Oncology (SOHO)?

Rami Komrokji, MD, of the Moffitt Cancer Center in Tampa, Florida, and 2024-2025 SOHO President Phillip Scheinberg, MD, PhD, of the Hospital Sao

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Meetings / Conferences 66th American Society of Hematology Annual Meeting & Exposition Lymphoma

CtDNA levels could serve as an early predictor of treatment success in LBCL

CtDNA is a valuable biomarker for monitoring disease burden and predicting durable clinical benefit in second-line large B-cell lymphoma (LBCL) treatment, according to

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