October 27, 2026
Meetings / Conferences SOHO 2026 Multiple Myeloma News

Arlo-cel, an anti-GPRC5D CAR T-cell, achieves deep and durable responses for patients with relapsed or refractory multiple myeloma in phase 1 trial

Final results from the first-in-human phase 1 study of arlo-cel represent the longest follow-up with GPRC5D CAR T-cell therapy in relapsed or refractory

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Meetings / Conferences SOHO 2026 MDS News News

Analysis shows marked difference in treatment patterns, survival between MDS risk groups

The study, led by Raúl Azibeiro Melchor, of Hospital Universitario de Salamanca in Spain, will be presented at the Fourteenth Annual Meeting of

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Meetings / Conferences SOHO 2026 MDS News

Telomere disorders linked to substantial morbidity, clonal hematopoiesis 

Patients with telomere biology disorders (TBDs) exhibited substantial hematologic and multiorgan morbidity as well as frequent clonal hematopoiesis with a high rate of

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Leukemia Acute Lymphoblastic Leukemia News

Extended analysis shows long-term benefit with obe-cel in relapsed or refractory B-ALL

The analysis, led by Elias Jabbour, MD, of University of Texas MD Anderson Cancer Center in Houston, was presented at the Fourteenth Annual

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Meetings / Conferences SOHO 2026 MDS News Myelodysplastic Syndromes News

Elritercept demonstrates effective, durable responses across LR-MDS subgroups

Elritercept, an investigational modified activin receptor type IIA ligand trap, was well-tolerated and associated with rapid, durable transfusion and erythroid responses, including in

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Meetings / Conferences SOHO 2026 MDS News Myelodysplastic Syndromes

Ofirnoflast improves transfusion burden, hemoglobin levels in LR-MDS

Ofirnoflast, a first-in-class allosteric NEK7 inhibitor, showed favorable safety and clinically significant efficacy in patients with low-risk myelodysplastic syndromes (LR-MDS) refractory to erythropoietin

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Meetings / Conferences SOHO 2026 MDS News News

Study characterizes excess mortality and survival factors in RS–positive MDS 

The study, led by Pina Gabriela Gálvez Zavala Registro, of Universidad Peruana Cayetano Heredia in Lima, Peru, compared patients in the Spanish Group

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Lymphoma Indolent B-Cell Lymphomas News

Mosunetuzumab plus response-adapted polatuzumab vedotin, obinutuzumab shows promise as chemotherapy-free option for indolent B-cell non-Hodgkin lymphoma

The investigators, led by Ryan C Lynch, MD, of Fred Hutchinson Cancer Center in Seattle, Washington, published their findings in the Journal of

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Cellular Therapy Leukemia Acute Myeloid Leukemia

Phase 1 data reported for anti-CD123 CAR T-cell therapy in relapsed or refractory AML, BPDCN 

The study’s authors, led by Lihua E Budde, MD, PhD, of City of Hope in Duarte, California, published the findings in the Journal

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Cellular Therapy Leukemia Acute Lymphoblastic Leukemia Meetings / Conferences EHA 2026

Nanobody-based anti-CD5 CAR T agent improves efficacy in relapsed or refractory T-cell ALL

The nanobody-based CD5 CAR T-cells had superior antigen-dependent activation compared with humanized CD5 CAR T-cells, said lead author, Jing Pan, MD, PhD, of

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