October 21, 2025
Society Updates

Virtual SOHO Breakthroughs in Blood Cancers meeting launches November 20

The new meeting offers an accessible format that meets the needs of busy hematologic oncologists, bringing the best in patient care knowledge directly

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News

EC approves obe-cel for relapsed or refractory B-ALL

The European Commission (EC) has granted marketing authorization to the chimeric antigen receptor T-cell therapy obecabtagene autoleucel (obe-cel; AUCATZYL) for adults ages 26

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Lymphoma Indolent B-Cell Lymphomas

EMA grants PRIME designation to Waldenstrom’s macroglobulinemia therapy BGB-16673

The European Medicines Agency (EMA) has granted  (PRIority MEdicines) designation to the investigational Bruton’s tyrosine kinase (BTK) degrader, BGB-16673, for the treatment of

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Acute Myeloid Leukemia

Investigational CPX-531 plus venetoclax may be a salvage therapy option for relapsed or refractory AML

A study assessed CPX-531 plus venetoclax in patients with relapsed or refractory acute myeloid leukemia (AML) and found that the combination was particularly

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Multiple Myeloma News

Triplet therapy maintains, improves quality of life in relapsed/refractory myeloma

The combination of belantamab mafodotin, bortezomib, and dexamethasone generally maintained or improved health-related quality of life (HRQOL) in patients with relapsed or refractory

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News

Study backs liso-cel as second-line treatment in transplant-ineligible LBCL

The final analysis from the phase 2 PILOT study showed that after a median of 18.2 months, response to lisocabtagene maraleucel (liso-cel) was

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Multiple Myeloma

Isatuximab approved in the EU for the treatment of transplant-eligible MM

The European Commission has approved isatuximab in combination with bortezomib, lenalidomide, and dexamethasone (VRd) for the induction treatment of adult patients with newly

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Acute Myeloid Leukemia Myelodysplastic Syndromes News

Combo eprenetapopt plus azacitidine is well-tolerated in TP53-mutated MDS and AML

A phase 2 study found that eprenetapopt plus azacitidine induced responses in patients with TP53-mutated myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). This

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Multiple Myeloma

Eque-cel receives Orphan Drug status for myeloma treatment in South Korea

South Korea’s Ministry of Food and Drug Safety (MFDS) granted Orphan Drug Designation to equecabtagene autoleucel (Fucaso; eque-cel) for adults with relapsed or

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Lymphoma Aggressive B-Cell Lymphomas News

FDA rejects glofitamab-GemOx sBLA in DLBCL

The US Food and Drug Administration (FDA) denied the supplemental Biologics License Application (sBLA) for glofitamab combined with gemcitabine and oxaliplatin (GemOx) for

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