FDA clears IND application for CD19/CD20 dual-targeting in vivo CAR-T therapy LB2501
LB2501 is the first known dual-targeting in vivo CAR-T therapy to receive FDA IND clearance. Built on the proprietary TaVec platform, the off-the-shelf,
LB2501 is the first known dual-targeting in vivo CAR-T therapy to receive FDA IND clearance. Built on the proprietary TaVec platform, the off-the-shelf,
Host Dr. Loretta Nastoupil also discusses with Dr. Xavier how to navigate second-line regimens like monoclonal antibodies versus bispecific T-cell engagers and manage
Offering practical advice for community physicians on managing toxicities while maintaining efficacy, Dr. Nooka explained how to modify standard schedules.
"This approval is grounded in data from BRUIN CLL-313, which showed a significant delay in disease progression for pirtobrutinib compared to chemoimmunotherapy, along
The discussion highlights key findings, including a significant improvement in spleen volume response for the selinexor-plus-ruxolitinib combination arm alongside similar symptom relief across
“...these are ... complementary regimens that could be given to suitable patients,” Dr. Dimopoulos said, explaining how DREAMM-7 fits patients progressing on lenalidomide
Building upon its previous approval in the relapsed or refractory setting, this expanded indication is based on data from the global phase 3
“… where is the threshold where you can get really good MRD negativity, good responses in this older patient population without causing ocular
The Society of Hematologic Oncology is proud to highlight some of the exceptional clinicians and researchers participating in the SOHO 2026 Young Investigator
SOHO 2027 is scheduled for August 25–28, 2027, in Houston, Texas at the George R. Brown Convention Center.