FDA grants orphan drug designation to EO2463 to treat indolent non-Hodgkin lymphoma
The US Food and Drug Administration has granted Orphan Drug Designation to EO2463 immunotherapy for the treatment of patients with indolent non-Hodgkin lymphoma
Lymphoma
Indolent B-Cell Lymphomas
Mantle Cell Lymphoma
News
AACR 2026
Cellular Therapy
Video Interviews
Tri-specifc CAR-T shows early activity in B-cell malignancies
The Phase 1 trial evaluates DuoCAR20.19.22-D95 in adults with relapsed or refractory B-cell malignancies who have often failed prior CAR T-cell treatments.
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Community Oncology
Leukemia
Myelodysplastic Syndromes
Video Interviews
What are the barriers to research in the community oncology setting?
In this session from the SOHO Insider Community Oncology Brown Bag series, Luke Fletcher, MD, presents on an exploration of barriers and solutions
AACR 2026
Cellular Therapy
Multiple Myeloma
News
Video Interviews
Drs. Ghobrial and Nadeem discuss results from the phase II CAR-PRISM trial
The discussion also covers the study's safety profile and the potential for these early-stage immunotherapies to achieve long-term curative results.
Leukemia
Acute Myeloid Leukemia
News
FDA approves oral combo for newly diagnosed AML
The oral combination is used with venetoclax for patients who are at least 75 years old or have other medical conditions that prevent
AACR 2026
Cellular Therapy
Video Interviews
Dr. Roy Jensen discusses POC CAR-T manufacturing
In this SOHO Insider interview from the 2026 AACR Annual Meeting, Roy Jensen, MD, vice chancellor and director of the University of Kansas
Myeloproliferative Neoplasms
Polycythemia Vera
Primary Myelofibrosis
News
FDA approves ruxolitinib extended-release tablets for MF, PV, and GVHD
The US Food and Drug Administration (FDA) has approved ruxolitinib (Jakafi XR) extended-release tablets for adults with intermediate or high-risk myelofibrosis and adults
Society Updates
Virtual SOHO Breakthroughs in Blood Cancers meeting returns November 12
In its second year, the Society of Hematologic Oncology (SOHO) will host its virtual SOHO Breakthroughs in Blood Cancers (SBBC) meeting, chaired by
Community Oncology News
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Community Oncology
News
Dr. Fletcher on barriers to sustaining research outside of academia
Dr. Luke Fletcher leads a discussion at 11:30 am CST on May 15, 2026, on exploration of barriers and solutions for activating and
Leukemia
Acute Myeloid Leukemia
Multiple Myeloma
News
China NMPA accepts IND application for novel bispecific in heme malignancies
The National Medical Products Administration (NMPA) of China accepted the investigational New Drug application for the immunotherapy 6MW5311, a LILRB4/CD3 T-cell engager bispecific