In this video interview from SOHO Asia 2026, Dr. Feng-Ming Tien discusses the critical link between the immune microenvironment and therapeutic success. He shares findings on how the interferon signaling pathway acts as a marker for whether a specific therapeutic agent will be effective in patients with acute myeloid leukemia and myelodysplastic syndromes.
Dr. Tien and his team found that many CD8 T cells appear more aged and behave more like NK cells, suggesting a weakened or altered immune environment. Patients who responded to treatment showed stronger immune signaling, including interferon pathways, compared with those who did not respond.
Dr. Tien was awarded for this particular abstract during a SOHO Asia session, shortly after he presented his research findings. The meeting was the first of its kind being held in Taipei, Taiwan, and Dr. Tien said it was an honor to be chosen to present his research.
Watch more videos from SOHO Asia on the SOHO Insider YouTube channel.
