Ingredient in popular energy drinks linked to leukemia growth
Taurine, an ingredient found in popular energy beverages like Red Bull, may promote leukemogenesis, according to findings published in Nature by Sonali Sharma,
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Fractionated var-cel induces deep remissions, has low incidence of CRS in patients with B-ALL
Var-cel was approved in 2021 in Spain for patients ages 25 years and older with relapsed or refractory B-cell precursor ALL.
Multiple Myeloma
Clinical trial criteria exclude over 40% of real-world patients with AL amyloidosis
In a letter published in HemaSphere, Claudia Bellofiore, MD, of the University of Pavia in Italy, and colleagues highlighted the need to expand
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Smoldering MM trends data show increased incidence in certain patient populations
A Letter to the Editor published in the American Journal of Hematology by Rong Wang, PhD, of Yale University, and colleagues is the
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Aggressive B-Cell Lymphomas
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Study shows PRO data are important component of treatment efficacy, tolerability assessment
Researchers used data from the POLARIX study to compare patient-reported outcomes (PROs) against clinician-reported adverse event (AE) data and found that several AEs
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Talquetamab, teclistamab combo induces responses in patients with extramedullary myeloma
“These results show clinical benefit from this off-the-shelf, bispecific antibody combination and validate dual targeting of GPRC5D and BCMA with talquetamab plus teclistamab
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Pirtobrutinib significantly improves PFS in patients with treatment-naïve CLL/SLL
Data from a late-breaking abstract presented by Wojciech Jurczak, MD, PhD, of the Maria Sklodowska-Curie National Research Institute of Oncology in Poland, at
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‘Promising’ early-phase results seen with KLN-1010, an off-the-shelf in vivo CAR-T for myeloma
Preliminary phase 1 results of the inMMyCAR trial showed “promising clinical activity and manageable toxicities” associated with the investigative chimeric antigen receptor (CAR)
Multiple Myeloma
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Teclistamab plus daratumumab improves survival compared with SOC triplet therapy in relapsed/refractory MM
A phase 3 study observed “clinically remarkable” outcomes with the combination of teclistamab and daratumumab in patients with relapsed/refractory multiple myeloma (MM). At
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Phase 3 study finds fixed-duration treatment non-inferior to continuous treatment in CLL
A study compared the mainstay treatment approaches for chronic lymphocytic leukemia (CLL) and found that fixed-duration regimens were non-inferior to continuous treatment, offering