July 30, 2025
Lymphoma Mantle Cell Lymphoma News

FDA approves acalabrutinib plus chemoimmunotherapy in previously untreated MCL

Acalabrutinib, a Bruton tyrosine kinase (BTK) inhibitor, has been approved in the United States in combination with bendamustine and rituximab for the treatment

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Leukemia Chronic Myeloid Leukemia

IND approved in Korea for CML treatment KF1601

An Investigational New Drug (IND) application for KF1601, a chronic myeloid leukemia (CML) treatment was submitted to and approved by the Korea Ministry

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Leukemia Acute Myeloid Leukemia Myelodysplastic Syndromes News

FDA grants fast track designation to LYT-200 in AML

The US Food and Drug Administration (FDA) has granted fast track designation to LYT-200 for the treatment of acute myeloid leukemia (AML). LYT-200

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Cellular Therapy Lymphoma

CAR-NK cell therapy FT596 ‘well tolerated’ in phase 1 trial

FT596, a CD19-directed chimeric antigen receptor (CAR) natural killer (NK) cell therapy, was well tolerated in patients with relapsed or refractory B-cell lymphoma

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66th American Society of Hematology Annual Meeting & Exposition Myeloma News Video Interviews

Refining progression criteria in relapsed myeloma

Jean-Sébastien Claveau, MD, of Maisonneuve-Rosemont Hospital at the University of Montreal, spoke with SOHO Insider at the 66th American Society of Hematology Annual

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Cellular Therapy Multiple Myeloma News

Do older patients with myeloma respond as well to ide-cel as younger patients?

“[T]hese findings provide reassurance that older adults treated with ide-cel, including frail patients, experience comparable efficacy to younger patients,” the authors wrote.

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Multiple Myeloma News Society Updates

Message from Editor-in-Chief Dr. Lonial: Advancing care amid uncertainty

May you live in interesting times…. You may have encountered this adage at some point in your life, though its origins are difficult

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Myeloproliferative Neoplasms Primary Myelofibrosis

Do driver mutations influence treatment outcomes in myelofibrosis?

The absence of cancer-related mutations 30 days after a transplant in patients with myelofibrosis might be more effective in measuring treatment response than

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66th American Society of Hematology Annual Meeting & Exposition Myeloma

Researchers call for ‘evidence-based’ driving restrictions for patients treated with CAR-T therapy

Driving restrictions for blood cancer patients undergoing chimeric antigen receptor (CAR)-T cell therapy may need reconsideration.

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Leukemia Myelodysplastic Syndromes

FDA approves imatinib oral solution to treat leukemia, other cancers

The US Food and Drug Administration (FDA) has approved imatinib (Imkeldi) oral solution to treat leukemia and other cancers. Imatinib is an advanced

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