July 14, 2025
EHA 2025

Pediatric-inspired Ph– ALL protocol reduces toxicity without improving survival

Researchers introduced a pediatric-inspired treatment protocol at their institution for patients with Philadelphia-negative (Ph–) acute lymphoblastic leukemia (ALL) and found that overall survival

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Lymphoma Indolent B-Cell Lymphomas News

FDA approves tafasitamab combo therapy for relapsed or refractory follicular lymphoma

The US Food and Drug Administration (FDA) has approved tafasitamab-cxix, a humanized Fc-modified cytolytic CD19-targeting monoclonal antibody, in combination with rituximab and lenalidomide

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EHA 2025

Post-CAR-T recovery of T cell, NK cell counts predicts long-term prognosis in B-ALL

Early recovery of specific T-cell counts and natural killer (NK) cell counts after CD19 chimeric antigen receptor (CAR)-T therapy can be used as

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EHA 2025 Meetings / Conferences News

Study supports recommendation that pregnancy be avoided in women taking ponatinib

A small study found that among pregnancies in which the mother was exposed to ponatinib, cases of Hirschsprung’s disease (HD) occurred. Paternal exposure

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News

Study finds ropeginterferon alfa-2b is ‘superior’ 2nd-line treatment for essential thrombocythemia

A study compared second-line treatment options for essential thrombocythemia (ET) and found that ropeginterferon alfa-2b “outperformed” anagrelide in both efficacy and safety outcomes.

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EHA 2025

Longer-term follow-up demonstrates efficacy of nemtabrutinib for refractory FL

Follow-up results from the BELLWAVE-003 study assessing nemtabrutinib in patients with hematologic malignancies showed continued antitumor activity and no new safety concerns with

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EHA 2025 Meetings / Conferences Myeloproliferative Neoplasms

Dr. Kuykendall from EHA 2025: ‘the research is as hot as the conference center’

Andrew Kuykendall, MD, SOHO Insider MPN podcast host, and assistant professor in the Department of Malignant Hematology at Moffitt Cancer Center, delivers live

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EHA 2025 News

FELIX post-hoc data reinforce obe-cel durability

A post-hoc analysis found that the chimeric antigen receptor T-cell therapy obecabtagene autoleucel (obe-cel) produced durable remissions and maintained a favorable benefit-risk profile

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Leukemia Young Investigator Program

Dr. Gonzalez Lugo reflects on the SOHO YIP award

Meet Jesus Gonzalez Lugo, MD, an assistant professor of medicine at the University of Kansas and a 2024 SOHO Young Investigator Program (YIP)

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Leukemia Acute Myeloid Leukemia

New immunotherapy approach may treat aggressive AML, MDS

Researchers conducted a proof-of-concept study for genetically redirecting T cells, offering a potential immunotherapy target for acute myeloid leukemia (AML) and myelodysplastic syndromes

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