March 29, 2026
Leukemia Acute Lymphoblastic Leukemia

FDA grants breakthrough designation to CAR-T therapy sofi-cel

Sofi-cel, an allogeneic, off-the-shelf, CD7-targeted CAR-T cell therapy, has previously received regenerative medicine advanced therapy, fast track, orphan drug, and rare pediatric disease

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Multiple Myeloma News

FDA clears IND for KLN-1010 in relapsed or refractory myeloma

The United States Food and Drug Administration cleared the Investigational New Drug application for KLN-1010, an in vivo BCMA-targeted CAR-T therapy, for patients

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Lymphoma Aggressive B-Cell Lymphomas News

Malaysia regulatory agency approves supplemental NDA for selinexor in relapsed or refractory DLBCL

The Malaysian National Pharmaceutical Regulatory Agency approved selinexor (XPOVIO) for adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) after at

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ASH 2025 Myelodysplastic Syndromes

Dr. Garcia-Manero presents phase 2 ASTX030 results in MDS and other blood cancers

n this video interview with SOHO Insider, Guillermo García-Manero, MD, professor and chief of the Section of Myelodysplastic Syndromes and ad interim chair

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Lymphoma Roundtable ASH 2025 Cellular Therapy Lymphoma Aggressive B-Cell Lymphomas Indolent B-Cell Lymphomas Roundtable Discussions Video Interviews

What are the therapeutic combinations in large cell lymphoma?

In this video, the group discusses adding novel agents to frontline chemotherapy in large B-cell lymphoma, including polatuzumab vedotin with R-CHOP and bispecific

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ASH 2025 Myeloma

Novel protein degraders target myeloma

In this video interview with SOHO Insider, Pan-Yu Chen, PhD, associate director of Translational Medicine at Opna Bio, presents her ASH abstract on

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SOHO 2026 Multiple Myeloma News Society Updates

Facing 2026 with a mix of inspiration and trepidation

"We have so much potential, so many lives dedicated to treatment and prevention of blood cancers, terabytes of data on immune function and

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Trending now ASH 2025 Myeloproliferative Neoplasms Primary Myelofibrosis

Adam Mead, MD, on interim phase 1 PROMise trial results in myelofibrosis

In this video interview with SOHO Insider, Adam Mead, MD, professor of hematology at the University of Oxford and lead author on the

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