August 27, 2025
News SOHO Insider Podcast

Drs. Kuykendall and Gerds discuss myelofibrosis anemia challenges

SOHO Insider MPN podcast host Andrew Kuykendall, MD, assistant professor in the Department of Malignant Hematology, Moffitt Cancer Center, and guest  Aaron Gerds,

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Lymphoma Indolent B-Cell Lymphomas

Poor outcomes in a subgroup of follicular lymphoma prompts need for personalized treatment approach

Prior studies have shown conflicting outcomes for patients with different follicular lymphoma (FL) grade subtypes. A recent study by Patrizia Mondello, MD, PhD

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Leukemia Chronic Lymphocytic Leukemia

Birelentinib granted Fast Track designation by FDA for CLL/SLL

The US Food and Drug Administration granted Fast Track Designation to birelentinib (DZD8586), a first-in-class lymphocyte-specific protein tyrosine kinase/Bruton’s tyrosine kinase (LYN/BTK) dual

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Lymphoma Aggressive B-Cell Lymphomas

ctDNA outperforms conventional measures in predicting remission after frontline LBCL treatment

Following frontline treatment for large B-cell lymphoma (LBCL), ultrasensitive circulating tumor DNA (ctDNA) is more prognostic of disease progression than conventional PET scans

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Society Updates

SOHO EAGLE program takes off, expanding access to education globally

EAGLE, which stands for Exchange for Advanced Global Learning and Education, fulfills SOHO’s longstanding mission to educate and to expand global access to

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News

SNDA submitted to FDA for venetoclax, acalabrutinib combo in CLL

The US Food and Drug Administration (FDA) received the supplemental New Drug Application for venetoclax (VENCLEXTA) and acalabrutinib (Calquence), an all-oral, fixed-duration regimen,

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Acute Myeloid Leukemia Myelodysplastic Syndromes

Treatment post-relapse improves survival outcomes in patients with AML or MDS

A real-world study assessed outcomes in patients with acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) who relapsed following transplant and observed a

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Multiple Myeloma

BELLINI trial does not show overall survival benefit for venetoclax versus placebo in myeloma

Final results of the phase 3 BELLINI trial showed no improvement in overall survival (OS) for patients with multiple myeloma (MM) when venetoclax

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Lymphoma Multiple Myeloma News

FDA approves biosimilar tocilizumab‑anoh for treatment of CRS

The US Food and Drug Administration (FDA) has approved an expanded indication of the intravenous (IV) formulation of tocilizumab-anoh to include in the

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SOHO 2025 Meeting News Society Updates

Nothing beats SOHO in Houston in September

 Register today at soho.click/2025. Become a member at soho.click/join.  

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