June 30, 2025
News

Study finds ropeginterferon alfa-2b is ‘superior’ 2nd-line treatment for essential thrombocythemia

A study compared second-line treatment options for essential thrombocythemia (ET) and found that ropeginterferon alfa-2b “outperformed” anagrelide in both efficacy and safety outcomes.

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EHA 2025

Longer-term follow-up demonstrates efficacy of nemtabrutinib for refractory FL

Follow-up results from the BELLWAVE-003 study assessing nemtabrutinib in patients with hematologic malignancies showed continued antitumor activity and no new safety concerns with

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EHA 2025 Meetings / Conferences Myeloproliferative Neoplasms

Dr. Kuykendall from EHA 2025: ‘the research is as hot as the conference center’

Andrew Kuykendall, MD, SOHO Insider MPN podcast host, and assistant professor in the Department of Malignant Hematology at Moffitt Cancer Center, delivers live

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EHA 2025 News

FELIX post-hoc data reinforce obe-cel durability

A post-hoc analysis found that the chimeric antigen receptor T-cell therapy obecabtagene autoleucel (obe-cel) produced durable remissions and maintained a favorable benefit-risk profile

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Leukemia Young Investigator Program

Dr. Gonzalez Lugo reflects on the SOHO YIP award

Meet Jesus Gonzalez Lugo, MD, an assistant professor of medicine at the University of Kansas and a 2024 SOHO Young Investigator Program (YIP)

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Leukemia Acute Myeloid Leukemia

New immunotherapy approach may treat aggressive AML, MDS

Researchers conducted a proof-of-concept study for genetically redirecting T cells, offering a potential immunotherapy target for acute myeloid leukemia (AML) and myelodysplastic syndromes

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2025 ASCO

Isatuximab with KRd boosts sustained MRD negativity in myeloma

Patients with newly-diagnosed multiple myeloma (MM) treated with isatuximab plus carfilzomib, lenalidomide, dexamethasone (IsaKRD) in induction, consolidation, and light consolidation phases saw sustained measurable

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2025 ASCO Meetings / Conferences

Phase 3 VERIFY study shows rusfertide significantly improves PV outcomes over SOC

In patients with polycythemia vera (PV) receiving standard of care (SOC) therapy, treatment with rusfertide resulted in a statistically significant reduction in the

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2025 ASCO

Sintilimab plus ICE regimen significantly improves complete remission in classical Hodgkin lymphoma

Sintilimab plus ifosfamide, carboplatin, and etoposide (ICE) as second-line treatment of classical Hodgkin lymphoma (cHL) significantly improved complete remission rates (CRRs) compared with

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Leukemia Chronic Myeloid Leukemia

Generic version of nilotinib enters US market for treatment of certain leukemias

A generic version of nilotinib (Tasigna®) entered the US market on May 27, 2025, with 180 days of exclusivity, reported Apotex, the pharmaceutical

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