February 16, 2026
Leukemia Myelodysplastic Syndromes News

Is unrelated cord blood better than bone marrow in haploidentical transplantation?

Haploidentical transplantation combined with unrelated cord blood resulted in superior one-year disease-free survival compared with the same transplant using bone marrow in patients

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Cellular Therapy Lymphoma Indolent B-Cell Lymphomas News

Liso-cel receives positive CHMP opinion in relapsed or refractory follicular lymphoma

The Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has recommended approval of lisocabtagene maraleucel (lise-cel) for

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Leukemia Chronic Lymphocytic Leukemia

Longer-term ALPINE results show ‘sustained PFS benefit’ with zanubrutinib for CLL/SLL

After a median follow-up of 42.5 months, zanubrutinib resulted in a sustained progression-free survival (PFS) benefit compared with ibrutinib, with responses deepening over

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Lymphoma Mantle Cell Lymphoma T-Cell Lymphoma

FDA grants Orphan Drug Designation to CD5-targeted CAR-T cell therapy for T-cell lymphoma

The US Food and Drug Administration (FDA) granted Orphan Drug designation to MB-105, a CD5-targeted chimeric antigen receptor (CAR)-T cell therapy, for the

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Leukemia Acute Myeloid Leukemia News

Bone marrow microenvironment boosts AML patients’ response to donor lymphocyte infusion

Differences in the bone marrow microenvironment may determine why some relapsed acute myeloid leukemia (AML) patients respond better to donor lymphocyte infusion (DLI)

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Myeloproliferative Neoplasms Primary Myelofibrosis

Is SVR linked to survival benefit in pacritinib-treated patients with myelofibrosis?

A study found that “pacritinib may offer a unique survival advantage” for patients with myelofibrosis (MF) and thrombocytopenia who achieve any spleen volume

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Cellular Therapy Multiple Myeloma News

CARTITUDE-4 findings show improved health-related quality of life with cilta-cel for multiple myeloma

Results of the CARTITUDE-4 trial assessing patient-reported outcomes in those with multiple myeloma receiving the chimeric antigen receptor (CAR) T-cell therapy ciltacabtagene autoleucel

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66th American Society of Hematology Annual Meeting & Exposition MDS

Preliminary TakeAim data shows promise of emavusertib in higher-risk MDS

The IRAK-4 inhibitor emavusertib showed encouraging clinical activity in patients with higher-risk myelodysplastic syndromes (MDS), according to preliminary data from the phase 1/2

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Lymphoma Aggressive B-Cell Lymphomas News

Presence of circulating lymphoma cells a significant adverse risk factor in DLBCL

The largest study to date evaluating the impact of circulating lymphoma cells (CL) on outcomes in patients with newly diagnosed de novo diffuse

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Myeloproliferative Neoplasms Polycythemia Vera

Orphan Drug Designation granted to selective JAK2 inhibitor for treatment of polycythemia vera

he US Food and Drug Administration (FDA) has granted orphan drug designation for VGT-1849A, a selective antisense oligonucleotide (ASO)-based JAK2 inhibitor for the

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