June 19, 2026
Multiple Myeloma

A modified quadruplet therapy is feasible for older, transplant-ineligible MM patients

The combination of isatuximab, bortezomib, and lenalidomide with limited dexamethasone is a feasible treatment option for transplant-ineligible older patients with multiple myeloma (MM),

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Lymphoma News

Interim PET scan after 4 treatment cycles predicts outcomes in primary mediastinal B-cell lymphoma patients

An interim positron emission tomography (PET) scan after four treatment cycles emerged as the strongest predictor of outcomes for primary mediastinal B-cell lymphoma

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Lymphoma

FDA clears Ventana hematopathology test for diagnosing BCL

The US Food and Drug Administration (FDA) has granted clearance to the Ventana Kappa and Lambda Dual ISH mRNA Probe Cocktail, an in-situ

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Leukemia Chronic Lymphocytic Leukemia

China NMPA approves phase 3 trial for ICP-248, orelabrutinib in CLL/SLL

The Center for Drug Evaluation (CDE) of the China National Medical Products Administration (NMPA) has approved a phase 3 clinical trial for ICP-248

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Myeloproliferative Neoplasms

Addition of ropeginterferon alfa-2b to standard PV care is cost effective

The addition of ropeginterferon alfa-2b (ropegIFNα) to phlebotomy for the treatment of polycythemia vera (PV) was “cost effective,” according to an Austrian study

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Multiple Myeloma

FDA grants Orphan Drug Designation for small-molecule MM therapy

The US Food and Drug Administration (FDA) has granted Orphan Drug Designation for OPN-6602, an oral small-molecule EP300/CBP inhibitor, for patients with multiple

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Lymphoma

FDA clears IND for novel relapsed or refractory NHL therapy

The US Food and Drug Administration (FDA) has cleared the Investigational New Drug (IND) application for LTZ-301, a first-in-class bispecific myeloid engager immunotherapy,

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Cellular Therapy Multiple Myeloma

Real-world study observes ‘superior’ outcomes with cilta-cel versus ide-cel for myeloma

A real-world study compared the two chimeric antigen receptor (CAR) T-cell therapies idecabtagene vicleucel (ide-cel) and ciltacabtagene autoleucel (cilta-cel) for the treatment of

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Cellular Therapy Leukemia Acute Lymphoblastic Leukemia Meeting News 2025 Tandem Meetings

Deeper MRD response associated with better survival in obe-cel-treated patients with B-cell ALL

Measurable residual disease (MRD) negativity was associated with better response to treatment with the chimeric antigen receptor T-cell therapy obecabtagene autoleucel (obe-cel) in

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Lymphoma

Japan regulatory body approves epcoritamab for relapsed or refractory follicular lymphoma

The Japan Ministry of Health, Labour and Welfare has approved epcoritamab (Epkinly) as a treatment for adult patients with relapsed or refractory follicular

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