July 1, 2025
Meetings / Conferences 66th American Society of Hematology Annual Meeting & Exposition News Roundtable Discussions MDS Roundtable

What are second line treatments in lower-risk MDS with anemia?

A roundtable discussion on anemia management in myelodysplastic syndromes, featuring moderator Guillermo Garcia-Manero, MD, of the University of Texas MD Anderson Cancer Center; Amy DeZern, MD, MHS, o f Johns Hopkins Medicine; Tiffany Tanaka, MD, of the University of California San Diego; and Uma Borate, MBBS, of Ohio State University, examines second-line therapies for MDS-related anemia. Key topics include the role of imetelstat, recently approved for transfusion-dependent patients post-erythropoiesis stimulating agent failure. The panel discusses imetelstat’s efficacy, thrombocytopenia risks, and uncertainties about its telomerase inhibition mechanism.

Watch more videos from the discussion.