July 1, 2025
Multiple Myeloma

Real-world study finds this triplet therapy is an option for daratumumab-refractory myeloma

A study showed that the triplet therapy isatuximab, pomalidomide, and dexamethasone (IsaPd) is an option for daratumumab-refractory multiple myeloma (MM), though the “modest”

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Leukemia News

EC approves blinatumomab in Ph-negative CD19+ B-ALL in the consolidation phase

By: Phillip McLeod The European Commission (EC) has approved blinatumomab (Blincyto) as a consolidation therapy for adult patients newly diagnosed with Philadelphia chromosome-negative,

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Meetings / Conferences 66th American Society of Hematology Annual Meeting & Exposition Myeloma News Video Interviews

Multiple myeloma updates with Dr. Lonial

In a video interview during the 66th American Society of Hematology (ASH) Annual Meeting and Exposition in San Diego, California, Sagar Lonial, MD,

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Leukemia Myelodysplastic Syndromes News

Is unrelated cord blood better than bone marrow in haploidentical transplantation?

Haploidentical transplantation combined with unrelated cord blood resulted in superior one-year disease-free survival compared with the same transplant using bone marrow in patients

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Lymphoma Indolent B-Cell Lymphomas News

Liso-cel receives positive CHMP opinion in relapsed or refractory follicular lymphoma

The Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has recommended approval of lisocabtagene maraleucel (lise-cel) for

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Leukemia Chronic Lymphocytic Leukemia

Longer-term ALPINE results show ‘sustained PFS benefit’ with zanubrutinib for CLL/SLL

After a median follow-up of 42.5 months, zanubrutinib resulted in a sustained progression-free survival (PFS) benefit compared with ibrutinib, with responses deepening over

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Lymphoma Mantle Cell Lymphoma T-Cell Lymphoma

FDA grants Orphan Drug designation to CD5-targeted CAR-T cell therapy for T-cell lymphoma

The US Food and Drug Administration (FDA) granted Orphan Drug designation to MB-105, a CD5-targeted chimeric antigen receptor (CAR)-T cell therapy, for the

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Leukemia Acute Myeloid Leukemia News

Bone marrow microenvironment boosts AML patients’ response to donor lymphocyte infusion

Differences in the bone marrow microenvironment may determine why some relapsed acute myeloid leukemia (AML) patients respond better to donor lymphocyte infusion (DLI)

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Myeloproliferative Neoplasms Primary Myelofibrosis

Is SVR linked to survival benefit in pacritinib-treated patients with myelofibrosis?

A study found that “pacritinib may offer a unique survival advantage” for patients with myelofibrosis (MF) and thrombocytopenia who achieve any spleen volume

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Multiple Myeloma News

CARTITUDE-4 findings show improved health-related quality of life with cilta-cel for multiple myeloma

Results of the CARTITUDE-4 trial assessing patient-reported outcomes in those with multiple myeloma receiving the chimeric antigen receptor (CAR) T-cell therapy ciltacabtagene autoleucel

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